Functioning Oxyphil Parathyroid Adenoma: A Case Report
Published: April 1, 2014 | DOI: https://doi.org/10.7860/JCDR/2014/.4297
Rajendra B Metgudmath, Vinita V Metgudmath, Prakash R Malur, Amal T Das, Anjali R Metgudmath
1. Associate Professor, Department of Otorhinolaryngology, Head and Neck Surgery, Jawaharlal Nehru Medical College, KLE University, Belgaum, Karnataka, India.
2. Assistant Professor, Department of Otorhinolaryngology, Head and Neck Surgery, Jawaharlal Nehru Medical College, KLE University, Belgaum, Karnataka, India.
3. Professor, Department of Pathology, Incharge Histo-Pathologist, K.L.E.S. Dr. Prabhakar Kore Hospital & M.R.C, KLE University, Belgaum, Karnataka, India.
4. Post Graduate, Department of Otorhinolaryngology, Head and Neck Surgery, Jawaharlal Nehru Medical College, KLE University, Belgaum, Karnataka, India.
5. Associate Professor, Department of General Medicine, Jawaharlal Nehru Medical College, KLE University, Belgaum, Karnataka, India.
Correspondence
Dr. Rajendra B Metgudmath,
95/c, Anugraha, Shanti-Nagar, M.G. Road, Tilakwadi, Belgaum-590006, Karnataka, India.
Phone: +919880327769, E-mail: drrajmet@yahoo.co.in
Oxyphil parathyroid adenomas are rare and clinical features of patients with this entity are not well defined. We are presenting a case of primary hyperparathyroidism with marked elevation of parathyroid hormone (PTH) and near normal calcium levels, that underwent parathyroidectomy. Histopathology revealed an oxyphil adenoma which showed positivity for PTH on immunohistochemical staining. Post – operatively, there was a significant decline in both PTH and alkaline phosphatase levels. Benign oxyphil adenomas may mimic parathyroid carcinomas, both in terms of clinical features and tumour size; and they should be considered in the differential diagnosis of patients with primary hyperparathyroidism.
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